This position satisfies two critical roles in the Company:
- Attending Veterinarian (“AV”) who, along with any consulting veterinarians and animal care staff, is responsible for the design, implementation, maintenance and oversight of an effective veterinary care program at MI Bioresearch. MI operates in a manner consistent with The Guide for the Care and Use of Laboratory Animals (“Guide”), NRC, 2011 and Public Health Service (“PHS”) policies as dictated by the Office of Laboratory Animal Welfare. And,
- Operations Safety Officer (“OSO”), who assures the Operations department is performing in a manner consistent with regulations in the context of overall safety. In this capacity, the OSO has direct responsibilities and is responsible for coordination of others to assure overall operational and employee safety.
Responsibilities of the incumbent include, but are not limited to:
- Assuring that the health of all animals is effectively monitored from entry to final disposition. This includes, but is not limited to:
- Assuring that programs are established, promoted and monitored that support the physical and psychological well-being of animals under MI’s responsibility;
- Assuring the appropriate number of people, including those in animal care and operations, are effectively trained at observing animals for clinical signs;
- Assuring all animals are observed at least daily;
- Providing and maintaining a system for reporting clinical conditions that might be due to infectious disease or are not recognized as a possible consequence in the approved VUF and assuring that same is properly used by all relevant personnel;
- Advising on and monitoring biohazard control policies and procedures relevant to the animal care and use program;
- Providing guidance on the disposition of animals with known or suspected opportunistic pathogens; and
- Providing ad hoc guidance on circumstances suggesting early animal euthanasia.
- Approval of all sources for animals supplied to MI. As the Company does not manage colonies internally, all subjects for research purposes are acquired from third-parties. The AV is responsible for:
- Establishing standards for validating the use of preferred vendors for sourcing animals;
- Periodically monitoring preferred vendors relative to those standards;
- Establishing exclusion criteria for animals entering an MI facility;
- Routinely monitoring preferred vendor performance;
- Assuring that all vendors communicate breaks in biosecurity to MI immediately upon occurrence; and
- Providing guidance for quarantine and testing of animals coming from sources other than preferred vendors.
- Guidance and oversight of animal husbandry. This involves the AV:
- Providing general oversight through review/approval of SOPs;
- Participating in facility inspections;
- Informing appropriate personnel of any changes in regulatory requirements or changes to the Guide that may affect animal care;
- Reviewing all protocols (VUFs) to assure that:
- consequences to animals are identified and action plans described.
- end point considerations are identified and action plans described.
- surgical procedures and perioperative care is addressed.
- pain and/or distress is identified and that protocols include adequate means to minimize pain and distress and give advice on relief of pain or distress not anticipated in the approved VUF.
- methods of euthanasia are consistent with those approved by the IACUC.
- Lead the Post Approval Monitoring to assure that criteria listed in the VUF (or protocol) are being followed; and
- Establish and audit for compliance the use of a reporting system to assure that any protocol-related consequence is identified and reported for observation/treatment.
- Engagement in the Company’s surgical programs, including assisting in development, training and validation of new surgical techniques. Surgery is a core competency within MI and one required to affect a number of cancer models. The AV is responsible for:
- Assuring that appropriate procedures/policies are in place to guide research investigators in developing protocols that include adequate surgical and perioperative care;
- Engaging in the development and validation of any new surgical techniques to assure compliance with then existing standards; and
- Participating in the training of personnel engaged in surgical procedures, as may be requested by Operations.
- Oversight of the proper use of anesthetics, analgesics and tranquilizing agents. Assure that procedures/policies are in place to guide research investigators in developing protocols that include appropriate methods of anesthetics, analgesics and tranquilizing agents that meet the requirements of the AVMA Guidelines (or any regulatory requirement that supersedes the AVMA Guidelines).
- Development and use of appropriate methods of euthanasia. Assure that procedures/policies are in place to guide research investigators in developing protocols that include appropriate methods of euthanasia that meet the requirements of the AVMA Guidelines (or any regulatory requirement that supersedes the AVMA Guidelines).
- IACUC membership. As a key leader in animal welfare at MI, the AV’s participation on the IACUC is critical and involves:
- Review of all SOPs and training related in any way to animal welfare;
- Review of all VUFs and protocols;
- Assisting the IACUC in developing appropriate guidelines relates to surgeries, use of anesthetics, analgesics and tranquilizing agents and in euthanasia:
- Participation in all Facilities Inspections and Program Reviews; and
- Direct engagement in advising the IACUC Chair and the IO on new regulations/Guide updates or deficient areas of the Program/facilities.
- Maintains currency in the field of laboratory animal medicine, particularly rodents, and changes in regulatory or guidance information that could affect the Company. This is accomplished through currency with literature, including publications by OLAW and AAALAC, engagement with peers and selective attendance at relevant meetings.
- Coordination with and oversight of all Company process that assure the safety and well-being of Operational employees, including chairmanship of the Company’s Safety Committee. This includes, but is not limited to:
- Assuring the Company has the proper processes and training to assure biosafety, including direct engagement with the Company’s third-party biosafety consultant;
- Assuring the Company has the proper processes and training to assure radiation safety, including direct engagement with the Company’s third-party biosafety consultant in collaboration with the imaging group leader;
- Assuring the Company has the proper processes and training to assure overall employee health and safety (“EHS”) in the laboratory and vivarium in collaboration with the person assigned EHS responsibilities; and
- Assuring the Company remains properly licensed with appropriate authorities including, but not limited to, NRC, Michigan Pharmacy Licensure, DEA Licensure, and in compliance with operating procedures associated with same.
- Must have a DVM (or VMD) from an accredited veterinary school in the United States. Training in laboratory animal medicine and has achieved board certification under the American College of Laboratory Animal Medicine is preferred/
- Minimum of 8-10 years’ experience in laboratory animal medicine.
- Must be licensed to practice veterinary medicine in Michigan. Under this person’s licensure, the AV should provide access to authorized veterinary pharmaceuticals and other veterinary supplies as requested.
- Strong interpersonal, organizational, analytical skills;
- Excellent communication (verbal and written) and listening skills;
- Problem-solving orientation;
- Independent actor, willing to assume responsibility and accountability
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