MI Bioresearch Annual AACR Event 2018
You are cordially invited to attend
MI Bioresearch’s Annual AACR Event 2018
Join us for a relaxing night under the stars to celebrate the advancements in cancer research each and every one of you have contributed to. We will be hosting our hospitality event at The Adler Planetarium. Take part in a delightful evening of hors d’oeuvres, drinks, and science.
Our guest speaker this year will be Charles G. Drake, MD, PhD. Dr. Drake is Director of Genitourinary Oncology and Co-Director of the Immunotherapy Program at New York-Presbyterian Columbia University Medical Center; and Associate Director for Clinical Research, Herbert Irving Comprehensive Cancer Center.
Dr. Drake is a nationally recognized physician-scientist with a Ph.D. in immunology, whose work focuses on understanding and fighting advanced-stage cancers with the immune system. He is known for rapidly incorporating discoveries made in the research lab into innovative clinical trials, including anti-tumor vaccines. His most recent work has focused on the body’s immunological response to radiation therapy and how immunotherapy and radiation therapy can be used in concert to treat cancer.
“Adaptive Treg Resistance in Cancer Immunotherapy”
Regulatory T cells (Treg) play an important role in attenuating the adaptive immune response to cancer, yet many open questions remain regarding the specificity and origin of tumor-infiltrating Treg. In both patients and pre-clinical models, the balance between CD8 effector T cells and Treg, the CD8/Treg ratio, correlates with outcome. In recent studies, we’ve found clear evidence in support of a mechanism we’ve termed “adaptive Treg resistance,” by which treatments that increase CD8 infiltration into tumors also lead to increased infiltration by regulatory T cells, such that the CD8/Treg ratio is challenging to alter. Accordingly, therapies designed to specifically deplete regulatory T cells show marked activity, particularly in combination with CD8-directed intervention. Some of these agents are being evaluated in Phase I studies, with the long-term goal being the development of more effective combination immunotherapy regimens.
6:00 – Check-in, Cocktail hour with hors d’oeuvres & drinks
7:00 – Program begins in the Sky Theater
7:15 – Introduction – Maryland Franklin, PhD, VP, Scientific Development, MI Bioresearch
7:30 – Guest Speaker Introduction – Dylan Daniel, PhD, Director, Scientific Development, MI Bioresearch
7:35 – Feature Presentation and Q&A – Charles G. Drake, MD, PhD, Columbia University Medical Center
8:15 – Closing Statements from MI Bioresearch
8:20 – Desserts and Drinks
9:00 – End time
Transportation To and From Our Event:
Complimentary transportation to our event and back to the McCormick Center Hotels and Downtown Chicago Loop Hotels will be provided by MI Bioresearch. There will be two 56-passenger buses continuously running from 5:30p-6:30p taking people from the McCormick Center (pick-up at Gate 26 on Level 1 of the South Bldg) to the Planetarium. After the event concludes at 9:00p, we will have one bus transporting people back to the hotels by the McCormick Center and one bus will transport people to the downtown Chicago loop area (Michigan Ave). Look for the buses from Windy City Limousine!