Sensitivity of Syngeneic Tumor Models to Focal Radiation

“Sensitivity of Syngeneic Tumor Models to Focal Radiation” Introduction and Background Use of image-guided focal irradiation is a mainstay of human cancer treatment. Image guidance allows for highly conformal treatment plans that minimize normal tissue toxicity and systemic response. With the advent of image-guided small animal irradiators such as the […]

A20: Modeling B Cell Lymphoma in Mice

Lymphomas represent a highly heterogenous set of lymphoid cell malignancies. They can originate from either B or T cells, but B cell-derived lymphomas, specifically non-Hodgkin lymphoma (NHL), are the most prevalent. Lymphomas can be diagnosed in children and adolescents, but incidence of lymphoma increases significantly with age, the median age of diagnosis being 67 years. […]

Focal Radiation in the Murine 4T1-luc2 Mammary Cancer Model

The use of immuno-oncology therapies have seen remarkable progress in the last five years and are currently undergoing clinical trial use in combination with a variety of agents including radiation therapy (RT).1 RT is a main-stay in clinical oncology treatments with approximately 60 percent of cancer patients receiving RT at some point during their care. […]

Access the Power of Focal Beam Radiation Using Xstrahl’s SARRP

Xstrahl’s SARRP (Small Animal Radiation Research Platform), incorporates CT imaging with precise radiation delivery to enable researchers to pinpoint an exact anatomical target. This small animal irradiator can then deliver single or multiple beams of radiation to the target with the upmost accuracy, matching the clinical techniques used in oncology […]